Abstract: Due to long-term operation under work conditions of high temperature, high pressure and high salt content, the equipment of offshore natural gas treatment platform has problems such as scaling and blockage. Disassembly and cleaning the equipment cost time and energy. Scaling analysis was carried out on the heat exchangers, automatic backwash filters, high temperature centrifugal pumps and other equipment which need frequent disassembly and cleaning. The problems of disassembly and cleaning equipment in the offshore natural gas treatment platform were solved through improvement measures including the optimization of cleaning agent, the design of online cleaning process and the transformation of sacrifical anode. This method can provide reference and promotion for other offshore gas field facilities to carry out such work.