Abstract: In order to inhibit the corrosion of industrial cooling water on the shell side of water cooler and improve the corrosion protection effect of water cooler, the simulation evaluation of protection effect of sacrificial anode protection and silicon aldehyde coating + sacrificial anode combined protection under different temperature conditions was carried out by using the combination of electrochemical test and boundary element simulation. The results showed that the cathodic protection current density required for the water cooler increased with the increase of temperature, and the cathodic protection current density required for the water cooler protected by the silicon aldehyde coating decreased significantly. The protection effect of the silicon aldehyde coating + sacrificial anode was better than that of sacrificial anode protection, and had little effect on the heat transfer efficiency of water cooler.