Abstract: The effects of chemical milling parameters such as stirring speed, solution ratio, placement position, chemical milling time, additive content, and chemical milling temperature on the microstructure of TA15 titanium alloy were investigated in this experiment, and the morphology of the allay was characterized by atomic force microscope (AFM). The results show that increasing the stirring speed, solution ratio, chemical milling time, and additives would make surface roughness of TA15 titanium alloy decreases. As the chemical milling temperature increased, surface roughness increased first and then decreased. The placement position had little effect on the surface roughness of TA15 titanium alloy.